Nothing quite like the classics. Yes that is Skeletor. Of course if he had looked like that in the original version there would be lots more frightened children in the 80s. This has happened to other 80s cartoon villains but this is one of the shiny ones. On the subject at hand, drawing from your childhood for campaign villains can be fairly inspired. Especially if you adapt them for the setting you're playing. Or not as the case may be. I have had requests to run He-man and She-Ra games before. Myself I'd be pulling inspiration from the likes of TMNT and possibly Darkwing Duck. Grabbing villains from the latter would be quite bizarre given the parody status of the show.
Art from here